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Won Taek Lee, M.D., Ph.D.

Professor
Department of Anatomy, Yonsei University College of Medicine
Sinchon-dong 134, Seodaemoon-Ku, Seoul 120-752, KOREA

inskull@yumc.yonsei.ac.kr

82-2-2228-1644, FAX 82-2-365-0700


Academic Position Held

2002. 3 - Present -------- Professor, Yonsei University College of Medicne

2000. 3 - 2004. 2 -------- Chairman, Dept. of Anatomy, Yonsei University College of Medicne

1995. 3 - 2002. 2 -------- Associate Professor, Yonsei University College of Medicne

1990. 3 - 1995. 2 -------- Assistant Professor, Yonsei University College of Medicne

1991. 11 - 1998. 11 ----- Executive Editor, Experimental Neurobiology

1987. 7 - 1989. 7 -------- Visiting Scientist, Dept. of Anatomy & Neuroscience, Marine Biomedical Institute

          University of Texas Medical Branch (UTMB), Galveston, Texas, U.S.A.

1987. 3 - 1990. 2 -------- Full Time Lecturer, Yonsei University College of Medicne

1986. 5 - 1987. 2 -------- Research Associate, Yonsei University College of Medicne

1983. 2 - 1986. 4 -------- Serve as a Army Captain, Teaching Staff (Anatomy), Korean Nursing Academy

1980. 3 - 1983. 2 -------- Teaching and Research Assistant, Yonsei University College of Medicne


Educational Backgraound

1980. 3 - 1987. 9 -------- Ph.D., Graduate School of Medicine, Yonsei University

1974. 3 - 1980. 2 -------- M.D., Yonsei University College of Medicine

1968. 3 - 1974. 2 -------- Daejon Middle and High School


Research Interest

- Morphological aspect of pain transmission of primary afferent neurons

- Effect of capsaicin on the morphology of central and peripheral nervous system


Publications

(Publications written in Korean are NOT included)

Mei Zi Yang, Jin Hee Mun, Yoon Jung Choi, Ja Hyun Baik, Won Taek Lee, Kyung Ah Park, Jong Eun Lee
Agmatine inhibits matrix metalloproteinase-9 via endothelial nitric oxide synthase. Neurol Res 2007 Jun 14; [Epub ahead of print] [Medline Abstract]

Jun Ho Jang, Kyung Hwa Kim, Taick Sang Nam, Won Taek Lee, Kyung Ah Park, Dong-Wook Kim, Joong Woo Leem
The role of uninjured C-afferents and injured afferents in the generation of mechanical hypersensitivity after partial peripheral nerve injury in the rat. Exp Neurol 204:288-298, 2007 [Medline Abstract]

Hokyou Lee, Jong Youl Kim, Jong Eun Lee, Won Taek Lee, Kyung Ah Park
Pyruvate reduces the necrotic but not apoptotic component of OGD/Reoxygenation injury in primary murine cortical neuronal cultures. Exp Neurobiol 16:9-17, 2007

In Sung Park, Jong Woo Han, Kea Joo Lee, Nam Joon Lee, Won Taek Lee, Kyung Ah Park, Im Joo Rhyu
Evalution of morphological plasticity in the cerebella of basketball player with MRI J Korean Med Sci 21:342-346, 2006 [Medline Abstract]

Won Taek Lee, Soo Kyung Ahn, Seung Hwa Park, Jong Eun Lee, Kyung Ah Park
Effects of capsaicin on the c-fos in the spinal dorsal horn and substance P- and CGRP-like immunoreactivities in the dorsal root ganglia of the experimental arthritic rat model. Exp Neurobiol 15:71-79, 2006

Won Taek Lee, Ho Yoon, Dong Joo Lee, Jong Eun Lee, Chul Hoi Koo, Kyung Ah Park
Effects of postnatally administered inorganic lead on the tyrosine hydroxylase immunoreactive norepinephrinergic neurons of the locus ceruleus of the rat. Arch Histol Cytol 65:45-53, 2002 [Medline Abstract]

Ju Hyun Cho, In Yup Park, Hun Sik Kim, Won Taek Lee, Mi Sun Kim, Sun Chang Kim
Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB J 16:429-31, 2002 [Medline Abstract]

Won Taek Lee, Sung Ho Lee, Sean G. Carreido, Rona G. Giffard, Yeon Jung Yoon, Ji Hyung Kim, Kyung Ah Park, Jong Eun Lee
UV-vulnarability of human papilloma virus type-16 E7-expressing astrocytes is associated with mitochondrial membrane depolarization and caspase-3 activation. Mol Cells 14:288-294, 2002 [Medline Abstract]

Youn-Woo Lee, Kyung Ah Park, and Won Taek Lee
Effects of MK-801 and morphine on spinal c-fos expression during the development of neuropathic pain. Yonsei Med J 43:370-376, 2002 [Medline Abstract]

Won Taek Lee, Jong Eun Lee, Sung Ho Lee, Hyun Sook Jang, Rona G. Giffard, and Kyung Ah Park
Human papilloma virus type 16 E7 genes protect astrocytes against apoptotic and necrotic death induced by hydrogen peroxide. Yonsei Med J 42:471-479, 2001 [Abstract] [Medline Abstract]

Won Taek Lee, Min Kyun Sohn, Seung Hwa Park, Soo Kyung Ahn, Jong Eun Lee, Kyung Ah Park
Studies on the changes of c-fos protein and neurotransmitter in dorsal root ganglion of the rat with an experimental peripheral neuropathy Yonsei Med J 42:30-40, 2001 [Abstract] [Medline Abstract]

Kim HS, Yoon H, Minn I, Park CB, Lee WT, Zasloff M, Kim SC.
Pepsin-mediated processing of the cytoplasmic histone H2A to strong antimicrobial peptide buforin I. J Immunol 165:3268-74, 2000 [Abstract] [Medline Abstract]

Won Taek Lee, Ho Yoon, Eun Jung Lee, Sung Ho Lee, Kyung Ah Park, Jong Eun Lee
Differential effects of intraganglionic capsaicin and vehicle on substance P- and CGRP-immunoreactive neurons in the rat dorsal root ganglia. Exp Neurobiol 8:99-105, 1999 [Abstract]

Jong Eun Lee, Won Taek Lee, Seung Hwa Park, Sung Ho Lee, and Kyung Ah Park
The effects of capsaicin on the ultrastructure of the hypothalamic neurosecretory cell in the adult rat. Exp Neurobiol 8:93-98, 1999 [Abstract]

JY Kwak, JY Jung, SW Hwang, WT Lee, U Oh
A capsaicin-receptor antagonist, capsazepine, reduces inflammation-induced hyperalgesic responses in the rat: Evidence for an endogenous capsaicin-like substance. Neuroscience 86:619-626, 1998 [Abstract] [Medline Abstract]

Won Taek Lee, Ho Yoon, Heung Dong Kim, Kyung Ah Park
Capsaicin induced changes on the substance P and CGRP immunoreactive nerve cell numbers and sizes in the dorsal root ganglion of the rat. Exp Neurobiol 5: 115-126, 1996 [Abstract]

Jong Eun Lee, Ki Sook Park, Won Taek Lee, Kyung Ah Park
Effect of capsaicin to the serotonergic neurons in the raphe nuclei of the rat midbrain. Exp Neurobiol 4: 127-134, 1995 [Abstract]

Ho Yoon, Won Taek Lee, Kyung Ah Park
Distribution of substance P and calcitonin gene-related peptide immunoreactive visceral afferent neurons in the dorsal root ganglia of the rat. Exp Neurobiol 3:29-38, 1994 [Abstract]

Kyungsoon Chung, Won Taek Lee, Mae Ja Park
Spinal Projections of Pelvic Visceral Afferents of the Rat: A Calcitonin gene-related Peptide (CGRP) immunohistochemical study. J Comp Neurol 337: 63-69, 1993 [Abstract] [Medline Abstract]

Won Taek Lee, Eun Sook Park, Jong Eun Lee, Ho Jung Kim, Kyung Ah Park
Distribution of first sacral primary afferent terminals immunoreactive to calcitonin gene-related peptide (CGRP) in the dorsal horn of the rat. Exp Neurobiol 2:33-41, 1993 [Abstract]

Jong Eun Lee, You Sun Kang, Won Taek Lee, Seung Jin Lee, Kyung Ah Park
The changes of the skeletal muscle fiber type after cross innervation of the rat by immunohistochemical study. Exp Neurobiol 2: 25-32, 1993 [Abstract]

Kyu Seok Lee, Ho Yoon, Jong Eun Lee, You Sun Kang, Kyung Ah Park, Won Taek Lee, Tai Sun Shin
Immunohistochemical and electronmicroscopical study of the myenteric plexus of the rat after capsaicin treatment. Exp Neurobiol 1: 21-27, 1992 [Abstract]

Won Taek Lee, Jong Eun Lee, Chang-Hyun Yang, Kyung Ah Park
Effect of neonatal capsaicin on the calcitonin gene-related peptide (CGRP) immunoreactive nerve fibers in the dorsal horn of the rat. Exp Neurobiol 1: 13-20, 1992 [Abstract]

John T Patterson, Richard E Coggeshall, Won Taek Lee, Kyungsoon Chung
Long ascending unmyelinated primary afferent axons in the rat dorsal column: Immunohistochemical localizations. Neurosci Lett 108: 6-10, 1990 [Abstract] [Medline Abstract]

Kyungsoon Chung, Won Taek Lee, Karin N Westlund
Adrenergic fibers in the spinal cord of the monkey: light and electron microscopic study. J Auton Nerv Syst 28: 203-210, 1989. [Abstract] [Medline Abstract]

Kyungsoon Chung, Won Taek Lee
Vasoactive intestinal polypeptide (VIP) immunoreactivity in the ependymal cells of the rat spinal cord. Neurosci Lett 95: 1-6, 1988. [Abstract] [Medline Abstract]

Kyungsoon Chung, Won Taek Lee, Suzan M. Carlton
The effect of dorsal rhizotomy and spinal cord isolation on calciton in gene-related peptide-labeled terminals in the rat lumbar dorsal horn. Neurosci Lett 90:27-32, 1988. [Abstract] [Medline Abstract]


Lecture Slides

Neuroanatomy Lecture Slides

Histology Lecture Slides